We design and execute your preclinical GLP/ non-GLP toxicology studies, ensuring the success of your drug/ health product development program while meeting global standards and specifications for quality and compliance

GENERAL IN VIVO TOXICOLOGY

• Acute Toxicity
• Sub-acute (28 days) toxicity
• Sub-chronic (90 days) toxicity
• Chronic Toxicity

SAFETY PHARMACOLOGY

• Central Nervous System – Irwin Test
• Cardiovascular System – hERG and Purkinje studies
• Respiratory System – whole body plethysmography

IN VITRO STUDIES

• Skin sensitization (OECD TG 442C,D,E)
• Skin absorption (OECD TG 428)
• Skin irritation (OECD TG 439)
• Eye irritation (OECD TG 492)
• Skin corrosion (OECD TG 431)
• Phototoxicity (OECD TG 432, 498)

GENOTOXICITY

• Bacterial Reverse mutation test (OECD TG 471, ICH S2 (R1)
• In vitro MicronucleousTest (OECD TG 487, ICH S2 (R1)
• Mammalian chromosome aberration in vitro – OECD TG 473