DRIVING FORCE

In drug development services

About us

Vector B2B – Drug Developing Association for Research in Biotechnology provides highly qualified services of drug discovery and development from the bench to bedside (B2B).

VectorB2B gathers the scattered capacities of the academic and industrial shareholders in the sector of health biotechnology to provide integrated services in drug discovery and screening, project design and implementation, pre-clinical and clinical scientific management, process development and contract manufacturing (GMP). The shareholders are a strong and complementary set of academic partners and biopharmaceutical companies renowned in the health sector in Portugal. Together, they form a robust asset of knowledge and innovation, particularly in the domain of biological therapeutics.

Vector B2B aims to be the driving force in drug development, helping our clients to develop their ideas and projects providing them with custom made solutions- “one stop shop”. Our approach is holistic, including strategy planning according to ICH guidelines, regulatory pathways, always aiming for fast time to market.

VectorB2B:

Gathering strengths, building capacity, innovating products, and far fetching in Drug Discovery and Development services

SERVICES PROVIDED

Drug Discovery

Generation of Fab, scFv, sdAb libraries

High throughput screening using robotized system

Antibody screening by phage display (in-vivo or ex-vivo)

Construction and testing of CAR-T cells

Reformatting Fab and scFv domains to human IgG

   

Molecular Biophysics
. Protein-protein and other solute-solute interactions (binding)
. Lipophiliticy / binding to lipid membranes
. Nanoparticles and aggregation dynamics

Cellular and Tissue Biophysics
. Cellular morphology and biomechanics
. Cellular membrane penetration
. Blood-barrier model translocation
. Intra-vital vessel imaging (rodent models)

Antibody services
. Affinity maturation
. Antibody engineering
. Antibody humanization
. ADCC and CDC testing

   

Antiretroviral efficacy (HIV-1)

Antibiotic efficacy (planktonic bacteria and pre-formed biofilms)

In vitro efficacy and toxicity tests using primary cell cultures, cell lines, tissue cultures and injury models
. Vision sciences
. Oncology
. Neurosciences

Target

Generation of Fab, scFv, sdAb libraries

High throughput screening using robotized system

Antibody screening by phage display (in-vivo or ex-vivo)

Construction and testing of CAR-T cells

Reformatting Fab and scFv domains to human IgG

Hit

Molecular Biophysics
. Protein-protein and other solute-solute interactions (binding)
. Lipophiliticy / binding to lipid membranes
. Nanoparticles and aggregation dynamics

Cellular and Tissue Biophysics
. Cellular morphology and biomechanics
. Cellular membrane penetration
. Blood-barrier model translocation
. Intra-vital vessel imaging (rodent models)

Antibody services
. Affinity maturation
. Antibody engineering
. Antibody humanization
. ADCC and CDC testing

Lead

Antiretroviral efficacy (HIV-1)

Antibiotic efficacy (planktonic bacteria and pre-formed biofilms)

In vitro efficacy and toxicity tests using primary cell cultures, cell lines, tissue cultures and injury models
. Vision sciences
. Oncology
. Neurosciences

Drug Development

In vivo efficacy and toxicity tests in rodent and companion animal models
. Vision sciences
. Oncology
. Neurosciences
. Liver diseases
. Infectious diseases

Access and testing of biobank samples

Pharmacokinetics using in vivo, in vitro and ex-vivo models

Process development of biologic products in microbial cultures- lab scale to bioreactor (8L)

GMP production up to 50L bioreactor scale

Formulation development

Management Consultancy for Clinical Development for Biotechs, Academic Institutions and Pharma Companies
. Regulatory strategy
. Clinical Solutions

Candidate

In vivo efficacy and toxicity tests in rodent and companion animal models
. Vision sciences
. Oncology
. Neurosciences
. Liver diseases
. Infectious diseases

Access and testing of biobank samples

Candidate

Pharmacokinetics using in vivo, in vitro and ex-vivo models

Candidate

Process development of biologic products in microbial cultures- lab scale to bioreactor (8L)

GMP production up to 50L bioreactor scale

Formulation development

Drug

Management Consultancy for Clinical Development for Biotechs, Academic Institutions and Pharma Companies
. Regulatory strategy
. Clinical Solutions

REQUEST QUOTE

ASSOCIATE MEMBERS

TECHNOPHAGE

Drug discovery & development company

(Click to read more)

MEDINFAR

Pharmaceutical Group focused on Galenic development, manufacturing,  distribution, marketing and sales

(Click to read more)

BEVAG

Consulting company in Management Systems

(Click to read more)

FML - UNIV. LISBOA

FML – Centro Cardiovascular
(Lisbon Academic Medical Center-Hospital de Santa Maria, FML, IMM)

(Click to read more)

FFL - UNIV. LISBOA

FFL – iMed – Research Institute for Medicines

(Click to read more)

FMV - UNIV. LISBOA

FMV – Center for Interdisciplinary Research in Animal Health

(Click to read more)

UNIVERSIDADE COIMBRA

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Careers

Production specialist

We are looking to hire: Production specialist   Essential Duties and Responsibilities include, but are not limited to, the following: Operate in the manufacture of biologic drug products for pre- clinical studies and clinical trials (upstream, downstream and fill...

Our News & Announcements

Bio-Europe Spring

Bio-Europe Spring

VectorB2B will be present at the 14th annual international partnering conference Bio-Europe Spring that will be held from 23rd to 25th of March at Paris Expo Porte de Versailles, Paris. It is the largest springtime biotech partnering event in Europe and a great...

PEGS Europe 2019, 18th-22nd November

PEGS Europe 2019, 18th-22nd November

This week we will be in Lisbon, at PEGS Europe, one of the largest European events that covers all aspects of protein and antibody engineering. Last edition, brought together 1,100 delegates from 36 countries, including 70% from pharma and biotech organizations....

Clients & Testimonials

Working with Vector B2B not only provided us with great data and thorough reports regarding the experiments we requested, but their scientific expertise helped optimize and improve the design of our experiments and success of our project. I definitely recommend engaging VectorB2B

Daniel Emerling

SVP Research, Atreca, Inc.

Contact us

13 + 10 =

VectorB2B

Drug Developing – Associação para Investigação em Biotecnologia

Address:
Av. Professor Egas Moniz,
Edifício Egas Moniz, 2º, Sala A8
1649-028 Alvalade – LISBOA

E-mail:
info@vectorb2b.com

Privacy Policy

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