DRIVING FORCE
In drug development services
About us
Vector B2B – Drug Developing Association for Research in Biotechnology provides highly qualified services of drug discovery and development from the bench to bedside (B2B).
VectorB2B gathers the scattered capacities of the academic and industrial shareholders in the sector of health biotechnology to provide integrated services in drug discovery and screening, project design and implementation, pre-clinical and clinical scientific management, process development and contract manufacturing (GMP). The shareholders are a strong and complementary set of academic partners and biopharmaceutical companies renowned in the health sector in Portugal. Together, they form a robust asset of knowledge and innovation, particularly in the domain of biological therapeutics.
Vector B2B aims to be the driving force in drug development, helping our clients to develop their ideas and projects providing them with custom made solutions- “one stop shop”. Our approach is holistic, including strategy planning according to ICH guidelines, regulatory pathways, always aiming for fast time to market.
VectorB2B:
Gathering strengths, building capacity, innovating products, and far fetching in Drug Discovery and Development services
SERVICES PROVIDED
Drug Discovery
Generation of Fab, scFv, sdAb libraries
High throughput screening using robotized system
Antibody screening by phage display (in-vivo or ex-vivo)
Construction and testing of CAR-T cells
Reformatting Fab and scFv domains to human IgG
Molecular Biophysics
. Protein-protein and other solute-solute interactions (binding)
. Lipophiliticy / binding to lipid membranes
. Nanoparticles and aggregation dynamics
Cellular and Tissue Biophysics
. Cellular morphology and biomechanics
. Cellular membrane penetration
. Blood-barrier model translocation
. Intra-vital vessel imaging (rodent models)
Antibody services
. Affinity maturation
. Antibody engineering
. Antibody humanization
. ADCC and CDC testing
Antiretroviral efficacy (HIV-1)
Antibiotic efficacy (planktonic bacteria and pre-formed biofilms)
In vitro efficacy and toxicity tests using primary cell cultures, cell lines, tissue cultures and injury models
. Vision sciences
. Oncology
. Neurosciences
Target
Generation of Fab, scFv, sdAb libraries
High throughput screening using robotized system
Antibody screening by phage display (in-vivo or ex-vivo)
Construction and testing of CAR-T cells
Reformatting Fab and scFv domains to human IgG
Hit
Molecular Biophysics
. Protein-protein and other solute-solute interactions (binding)
. Lipophiliticy / binding to lipid membranes
. Nanoparticles and aggregation dynamics
Cellular and Tissue Biophysics
. Cellular morphology and biomechanics
. Cellular membrane penetration
. Blood-barrier model translocation
. Intra-vital vessel imaging (rodent models)
Antibody services
. Affinity maturation
. Antibody engineering
. Antibody humanization
. ADCC and CDC testing
Lead
Antiretroviral efficacy (HIV-1)
Antibiotic efficacy (planktonic bacteria and pre-formed biofilms)
In vitro efficacy and toxicity tests using primary cell cultures, cell lines, tissue cultures and injury models
. Vision sciences
. Oncology
. Neurosciences
Drug Development
In vivo efficacy and toxicity tests in rodent and companion animal models
. Vision sciences
. Oncology
. Neurosciences
. Liver diseases
. Infectious diseases
Access and testing of biobank samples
Pharmacokinetics using in vivo, in vitro and ex-vivo models
Process development of biologic products in microbial cultures- lab scale to bioreactor (8L)
GMP production up to 50L bioreactor scale
Formulation development
Management Consultancy for Clinical Development for Biotechs, Academic Institutions and Pharma Companies
. Regulatory strategy
. Clinical Solutions
Candidate
In vivo efficacy and toxicity tests in rodent and companion animal models
. Vision sciences
. Oncology
. Neurosciences
. Liver diseases
. Infectious diseases
Access and testing of biobank samples
Candidate
Pharmacokinetics using in vivo, in vitro and ex-vivo models
Candidate
Process development of biologic products in microbial cultures- lab scale to bioreactor (8L)
GMP production up to 50L bioreactor scale
Formulation development
Drug
Management Consultancy for Clinical Development for Biotechs, Academic Institutions and Pharma Companies
. Regulatory strategy
. Clinical Solutions
REQUEST QUOTE
ASSOCIATE MEMBERS
TECHNOPHAGE
Drug discovery & development company
MEDINFAR
Pharmaceutical Group focused on Galenic development, manufacturing, distribution, marketing and sales
BEVAG
Consulting company in Management Systems
FML - UNIV. LISBOA
FML – Centro Cardiovascular
(Lisbon Academic Medical Center-Hospital de Santa Maria, FML, IMM)
FFL - UNIV. LISBOA
FFL – iMed – Research Institute for Medicines
FMV - UNIV. LISBOA
FMV – Center for Interdisciplinary Research in Animal Health
UNIVERSIDADE COIMBRA
CIBB
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Careers
Production specialist
We are looking to hire: Production specialist Essential Duties and Responsibilities include, but are not limited to, the following: Operate in the manufacture of biologic drug products for pre- clinical studies and clinical trials (upstream, downstream and fill...
Our News & Announcements
COVID-19 New Challenge: joint effort to mitigate world’s pandemic crisis
TechnoPhage S.A., Faculty of Pharmacy of University of Lisbon and Vector B2B – Drug Developing Association for Research in Biotechnology In Portugal, we have highly qualified human resources working in biological drug discovery and development. In a joint effort to...
Bio-Europe Spring
VectorB2B will be present at the 14th annual international partnering conference Bio-Europe Spring that will be held from 23rd to 25th of March at Paris Expo Porte de Versailles, Paris. It is the largest springtime biotech partnering event in Europe and a great...
PEGS Europe 2019, 18th-22nd November
This week we will be in Lisbon, at PEGS Europe, one of the largest European events that covers all aspects of protein and antibody engineering. Last edition, brought together 1,100 delegates from 36 countries, including 70% from pharma and biotech organizations....
Contact us
VectorB2B
Drug Developing – Associação para Investigação em Biotecnologia
Address:
Av. Professor Egas Moniz,
Edifício Egas Moniz, 2º, Sala A8
1649-028 Alvalade – LISBOA
E-mail:
info@vectorb2b.com
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