Toxicology

Sub-Chronic Toxicology

Sub-chronic toxicology types

Types of Studies

• 90 days with recovery period – GLP compliant

General Recommendations and Objectives

• The same recommendations relevant to sub-acute dose toxicology;
• 90-days studies provides information on the possible health hazards likely to arise from repeated exposure over a prolonged period of time;
• The study will provide information on the major toxic effects, indicate target organs and the possibility of accumulation of test chemical, and can provide an estimate of NOAEL;  
• This study provides dose response related data that may be used to estimate point of departure for hazard assessment using appropriate modelling methods.