In vitro assays

  • Evaluation of Minimum Inhibitory (MIC) and Minimum Bactericidal Concentration (MBC)
  • Antiviral drug screening under Biosafety Levels 2 and 3 (SARS-CoV-2; HIV-1; ZICA) using: Plaque assay (SARS-CoV-2 or ZICA); Medium Tissue Culture Infection Dose (TCID50) assay with luminescence readout (HIV-1)
  • Antiviral activity using tissue-specific cell lines as host cells (Vero CCL-81, Vero E6 or TZM-bl reporter cell line)
  • Determination of viral inhibition and dose-response analysis (IC50 value)
  • Custom-tailored biochemical (e.g. qRT-PCR) and cell-based assays
  • Evaluation of cytotoxicity and determination of CC50 value
  • Time-of-compound-addition (TOA) assay
  • Virus Yield Reduction assay
  • Evaluation of antiviral activity in textiles according to ISO18184:2019 (woven, fibres, yarns) and in plastics and non-porous materials according to ISO21702:2019 (surface coatings, paints, ceramics, stainless, rubbers)

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